Rasa Karpura is a well known and popular non-sulphur compound of Ayurvedic mercurial preparation. Chemically Rasa Karpura is a mercuric chloride. Highly toxic, corrosive to mucous membranes. Ingestion may cause severe nausea, vomiting, hematemesis, abdominal pain, diarrhoea, malena, renal damage, prostration. 1-2 gm is frequently fatal, poisoning and death also have occurred from intra uterine douches.
Toxicity study revealed that Mercuric Chloride in therapeutic doses proved to be least toxic. It must be used after its proper purification; otherwise it may be harmful or toxic for the body. After Shodhana of Rasa Karpura is used therapeutically for bacteriostatic and bactericidal effect. This Research work is completed in NIA, Jaipur in 2006.